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20 apr. 2022
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Hormone Replacement Hormone replacement therapy to make up for the body's diminished estrogen production will relieve the Australia Mobile Number Database severity and frequency of hot flushes and the vaginal dryness. At one time, long-term estrogen replacement was widely recommended for all women. In recent years, however, there has been an Australia Mobile Number Database shift in attitudes as more became known about possible risks of long-term estrogen therapy. Studies have linked estrogen replacement with an increased risk of gallbladder disease and cancer of the endometrium (the lining of the uterus). In the menstruating woman, fluctuating Australia Mobile Number Database levels of estrogen and progesterone stimulate the endometrium to grow in readiness for a fertilized egg. If conception does not take place, the hormone levels drop and the lining is shed in the form of a menstrual period. During uninterrupted Australia Mobile Number Database estrogen therapy, the endometrial tissue proliferates, but it Australia Mobile Number Database is not shed. Some researchers feel this unopposed estrogen stimulation is a factor in the increased occurrence of endometrial cancer Australia Mobile Number Database is seen in women on long-term estrogen replacement. These risks can be minimized, many experts feel, by using the smallest possible dose of estrogen that effectively Australia Mobile Number Database minimizes symptoms for as short a time as needed. Periodic endometrial biopsies also may be advised. Of course, the worry is moot for women who have undergone surgical removal of the uterus (hysterectomy), since they no longer have any Australia Mobile Number Database risk of endometrial cancer. In addition, a new approach has been developed that involves giving low doses of estrogen that are interrupted every month or two with a few Australia Mobile Number Database days of pregesterone. This, in effect, mimics the natural menstrual cycle and prevents the buildup of endometrial tissue. Women on this regimen will bleed as during a menstrual period, Australia Mobile Number Database even though the ovaries have ceased to function.
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